With Galactus defeated and Dr. Doom moping behind bars, Super Hero City is finally safe - that is, until Thanos goes in search of the powerful Infinity Gauntlet! Although they are without their comrade-in-laughter, Silver Surfer, the Super Hero Squad - Iron Man, Thor, Hulk, Wolverine and Falcon - must once again come together to take on any villain that threatens the peace and safety of the Marvel universe . . . no matter where it might take them!

Featuring the hilarious guest voice talents of Ty Burrell (Modern Family), John O'Hurley (Seinfeld), Stan "The Man" Lee, Jane Lynch (Glee), James Marsters (Buffy The Vampire Slayer) and Adam West (Family Guy)!